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Year : 2020  |  Volume : 4  |  Issue : 2  |  Page : 66-68

Beneficial effects of negative fluid balance in preventing global increased permeability syndrome of septic shock patient

1 Department of Anesthesiology and Intensive Care, Fatmawati Hospital, Jakarta Pusat, Indonesia
2 Trainee of Anesthesiology and Intensive Care Department, Faculty of Medicine, University of Indonesia, Jakarta Pusat, Indonesia

Correspondence Address:
Dr. Marilaeta Cindryani
Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 5, Senen, Jakarta Pusat
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/BJOA.BJOA_3_20

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Fluid is considered a successful tool for resuscitation based on the worldwide guideline for sepsis since 2001. However, recent publications have studied of a deleterious effect of overload in fluid resuscitation. Overload is suggested to contribute to many severe complications such as acute respiratory distress syndrome, acute kidney injury, and higher mortalities. About more than 10 years later, another theory emerged and successfully changing the whole paradigm. Sometimes we need to resuscitate, sometimes we need to hold, and sometimes we need to evacuate. Our patient had several advantages from a negative fluid balance to prevent deteriorating conditions.

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